PhD Position in Organic Chemistry and Synthetic Glycochemistry

PhD Position in the field of Organic Chemistry and Synthetic Glycochemistry

The PhD position is funded by FWF (Austrian Science Fund)

The work package focuses on the chemical synthesis of novel biologically active carbohydrates and glycoconjugates, chemical glycosylation and chemical synthesis of oligosaccharides, glycosyl phosphates and glycolipids. The project “Synthetic bioactive carbohydrates for studying inflammation and sepsis” has a strong biological background and is conducted in tight cooperation with multiple collaboration partners in the field of immunology, molecular and structural biology.

  • Applicants should hold a Master degree (or equivalent) in Organic Chemistry (Bioorganic chemistry) entitling to embark on doctoral studies. A background in the chemical synthesis of carbohydrates/oligonucleotides/peptides or natural product synthesis is advantageous. 
  • Strong interest in synthetic organic chemistry, good background in common analytical and purification methods (HPLC, FPLC, NMR), dedication to experimental work and a good command of written and spoken English is required.

We offer:

  • working in a well-equipped, innovative and scientifically stimulating surrounding
  • demanding, multi-faceted, creative job within an international team
  • The fellowship is available for 3 years and is within standard FWF salary range for graduates under full coverage of the Austrian social security system. Salary and additional benefits are according to FWF standards (https://www.fwf.ac.at/en/research-funding/personnel-costs/#c6541) and the University Collective Contract.

Applicants are asked to submit their CV, detailed description of their previous academic and scientific activities, a summary of master thesis (max 5 pages), a photo, and the names and contact addresses (e-mail) of two academic referees directly to Assoc. Prof. Dr. Alla Zamyatina: alla.zamyatina(at)boku.ac.at.

Application deadline 30.06.2019

Shortlisted candidates will be contacted for an interview.

Dept. of Chemistry & Dept. of Nanobiotechnology Glycochemistry Group

Pyruvylation of cell wall polymers is pivotal to sticking bacterial cell walls together. The project “Molecular basis of cell wall pyruvylation” funded by the FWF grant P 32521 (PIs: Christina Schäffer and Paul Kosma) is aimed at the chemical synthesis of defined secondary cell wall polymer fragments and biosynthetic intermediates, which will be used as acceptors for bacterial pyruvyltransferases, NMR and crystallographic studies.
Applicants should have a diploma or master degree in organic chemistry or a related discipline.


Strong interest in synthetic organic chemistry, experience in common analytical and purification methods (HPLC, MS, NMR) and dedication to experimental work lege artis documentation is required.


Offer:
The position (salary according to FWF personnel costs for graduates) will be available for 3 years from October 2019.

Information and application: Prof. Paul Kosma
Phone +43-1-47654-77355
E-mail: paul.kosma@boku.ac.at