Nature solved many problems, which industrial microbiologists encounter, when establishing microbial production processes. Natural adaptation to all possible ecological niches bred microorganisms, ready to tackle many industrial tasks. Our lab takes advantage of this natural biodiversity to find cell factories, which are as best as possible suited for the conditions, required by the industrial processes. We focus on chemical production from renewable resources to contribute to the development of a carbon neutral society.
Our lab’s philosophy is to combine natures diversity with synthetic biology, to develop bio-processes as close as possible to industrial realities. We employ bacteria, yeasts and filamentous fungi of different origins. Lactic acid bacteria are among our favorites as they combine extraordinary stress resistance with high carbon flux rates and low biomass formation.
For our synthetic approaches we are focusing on membrane transport phenomena. Compartmentalization is a basic principle of life. The minimal compartment is built by the cell membrane, dividing a hostile “outside” from the living “inside”. The decision, which compounds are transported in which direction is of utmost importance for the survival of any given cell. It is also of major interest for industrial microbiologists as substrate uptake and product export are limiting factors for bio-processes. Our lab is dedicated to understand transport mechanisms better and to make use of this knowledge for bio-process development.
Publications of this Research Group
Improvement of 3-hydroxypropionic acid tolerance in Klebsiella pneumoniae by novel transporter YohJK.
International Microorganism Day
CD-Lab for Biotechnology of Glycerol
The Plasma Membrane at the Cornerstone Between Flexibility and Adaptability: Implications for Saccharomyces cerevisiae as a Cell Factory
Lactic acid bacteria: little helpers for many human tasks.
Sclerotia formed by citric acid producing strains of Aspergillus niger: Induction and morphological analysis
Michael Sauer's Lectures
Utilizing yeasts for the conversion of renewable feedstocks to sugar alcohols - a review
Efficient conversion of hemicellulose sugars from spent sulfite liquor into optically pure L-lactic acid by Enterococcus mundtii
Michael Sauer, Assoc. Prof. Priv.-Doz. Dipl.Natw. ETH FH-Prof. Dr.
- H79200 Institut für Mikrobiologie und Mikrobielle Biotechnologie
- H79000 Department für Biotechnologie (DBT)
- H10240 Ethikplattform
- +43 1 47654-79105
Institut für Mikrobiologie und Mikrobielle Biotechnologie
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