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Research project (§ 26 & § 27)
Duration : 2019-01-02 - 2020-01-01

The biological information derived from the microbiome can help to answer crucial questions that may arise when dealing with valuable objects. A microbial pedigree can help to: • certificate the authenticity of an object, • to identify the biological material and microbial species of an artefact, • to get insights into the geographical origin of an artefact, • to get insights into the travel history of an object and into the storage conditions, • to group objects of unknown origin, • to decipher the usage of an object. The samples for performing microbial pedigrees will be provided by the Istituto Centrale per il Restauro e la Conservazione del Patrimonio Archivistico e Librario. Up to 6 cotton swabs or membrane samples will be taken from each object and will be pooled into one microbial pedigree analysis.
Research project (§ 26 & § 27)
Duration : 2018-12-01 - 2019-11-30

Demographic changes in the industrialized world lead to an increased occurrence of medical conditions, for which biological age is the major risk factor. In addition to arising complications and onset of multimorbidity due to decreased resilience, frailty severely limits the quality of life at advanced age. Thus, a better understanding of biological ageing processes will promote the design of interventions, which target biological ageing and thereby increase fitness, decrease frailty and improve resilience at advanced age. However, simple and cost-effective models of human healthspan are still missing. Thus, we will establish standardized and reproducible tests for evaluating mobility, memory and electrophysiology of ageing nematodes. With these methods we will evaluate if known interventions extending lifespan also improve physiology at advanced age.
Research project (§ 26 & § 27)
Duration : 2018-02-01 - 2019-01-31

The goal of the Project was the development and establishment of a suitable molecular protocol to obtain a genetic fingerprint (or “microbial pedigree”) of the microbial contaminants found in art and cultural heritage objects, -i.e. paintings and sculptures- using the Nanopore sequencing technology platform. The main purpose was to develop a protocol that was easy for the operator to use, fast and relatively low cost.

Supervised Theses and Dissertations