PhD Award for Nino Trattnig MSc. Dr. Nino Trattnig was presented with the GÖCh (Austrian Chemical Society) Award in recognition of his PhD thesis elaborated at the Department of Chemistry
MSc. Dr. Nino Trattnig was presented with the GÖCh (Austrian Chemical Society) Award in recognition of his PhD thesis elaborated at the Department of Chemistry.
The cumulative thesis entitled „Synthesis and vaccine potential of novel oligomannosides against HIV-1“ was carried out in the Division of Organic Chemistry in the framework of a project funded by the Austrian Science Fund FWF. Using synthetic organic chemistry, fragments of bacterial cell wall carbohydrates were combined with those of the viral surface followed by coupling of the ligands to proteins. These neoglycoconjugates showed promising properties in subsequent immunization studies. The work has been published in Nature Communications. The GÖCh awards are sponsored by the Assocation of the Austrian Chemical Industry.
In collaboration with research groups from Canada and the US, scientists of the Division of Organic Chemistry (Paul Kosma, Nino Trattnig) used chemical synthesis of modified carbohydrate structures related to the envelope of the HI-virus to induce HIV-neutralizing antibodies as reported in Nature Communications.
Here you will find the original publication in Nature Communications
... and here is the link to a radio show about this topic
The discovery of novel antibiotic compounds represents a current priority in health sciences, owing to the global emergency constituted by a growing resistance to currently used antibacterial therapies. The search for new compounds targeting receptors and pathways specific for bacteria – and not expressed on, or used by human cells – is therefore a fundamentally important research area. Recently, the group of Professor Paul Kosma at the University of Natural Resources and Life Sciences (Vienna, Austria) has reported the development of new potential molecular tools for tackling bacterial infections.