Our research group is investigating wholistic bioprocess development and engineering with a focus on plant molecular farming, i.e. the use of plants and plant cells to produce value-added products such as small molecule drugs and recombinant proteins.
Specifically, we perform
- Rational gene and protein design to improve food supplement, enzyme and therapeutic manufacturability
- Development of plants and plant cell cultures, to produce challenging and innovative products such as recombinant immunetoxins
- Bioprocess integration of upstream production, downstream processing and data analysis
- Cascading biomass utilization of waste and side streams for a sustainable integrated bio-economy
- Process modelling of expression and separation of products and host cell proteins using data-driven, mechanistic and hybrid models
- Process digitalization for model predictive control in bioengineering
- High-throughput screening and optimization for bio-transformation
Our research is embedded into joined activities with partners from academia and industry with whom we translate products and processes from bench to scalable, cost-efficient applications.
