790363 Immuno- and vascular biology in health and disease

Semester hours
Lecturer (assistant)
Kalic, Tanja , Hayer, Silvia , Breiteneder, Heimo
Offered in
Sommersemester 2024
Languages of instruction


Basics of the roles of the innate and adaptive immune system in allergy and autoimmune diseases will be covered. The classification of allergens by protein families will be introduced and the influence of protein engineering on the development of allergen vaccines will be explained. The impact of genetic influences, epigenetic modifications, miRNA profiles, autoantibodies and environmental triggers for Rheumatoid Arthritis, Systemic Lupus Erythematodes and Multiple Sclerosis will be discussed. Therapeutic strategies and future prospects in allergic and autoimmune diseases will be outlined. In the context of vascular biology, the blood and lymphatic system will be introduced. The role of endothelial cells in inflammation, coagulation and angiogenesis will be addressed and the corresponding pathological processes, e.g. atherogenesis, thrombosis, and macula degeneration, will be explained.

Objective (expected results of study and acquired competences)

After completion of this course the students understand the principles and pathomechanisms of allergic, autoimmune and vascular diseases and are able to identify and evaluate targets and strategies for therapies.
You can find more details like the schedule or information about exams on the course-page in BOKUonline.