790368 Biological therapeutics


Type
Lecture
Semester hours
2
Lecturer (assistant)
Radauer, Christian , Kunert, Renate
Organisation
Offered in
Wintersemester 2023/24
Languages of instruction
Englisch

Content

The lecture will take place in seminar room 05/08 in the 5th floor of MUG1/DBT.

If you have any organisational questions, please contact my colleague Christine Prenner (christine.prenner@boku.ac.at)

Kind regards
Renate Kunert

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Contents:

Biological Therapeutics overview
Human Erythropoietin
Human insulin
Therapeutic enzymes
Human growth hormone
Plasma fractionation
Structure and function of immunoglobulins
Development and production of therapeutic antibodies
Recombinant antibody derivatives
Inhibitors of tumor necrosis factor (TNF)
Anti-HER2 and anti-B cell antibodies
Angiogenesis inhibitors

Previous knowledge expected

students should have passed already the examination cell factories but at least need knowledge about generation of recombinant cell lines and propagation of cell culture

Objective (expected results of study and acquired competences)

After having passed the course the students are able
- to transform their scientific knowledge for the development of biological therapeutics
- to assess development strategies and critically evaluate the quality demands of products
- to rank the scale of the production effort for up-stream, down stream and formulation procedures
- to explain data gained by in vitro studies and propose the products behaviour in vivo.
You can find more details like the schedule or information about exams on the course-page in BOKUonline.