Dental implant research at BOKU


At the Institute for Synthetic Bioarchitectures, ceramic dental implant surfaces have been investigated for years. The aim is to improve the ingrowth behavior (osseointegration) through new surface architectures. Together with a dental implant manufacturer, we recently submitted a strategy for non-chemical surface modification as an international patent.

As part of the NanoEHS call, we have been given the opportunity to apply our previous knowledge to a specific question: how do potential abrasions of such ceramics behave? What tent biological effects do we see in our human cell lines and how do our findings compare to conservative dental implants?

 

At the Institute for Synthetic Bioarchitectures, ceramic dental implant surfaces have been investigated for years. The aim is to improve the ingrowth behavior (osseointegration) through new surface architectures. We have recently filed a strategy for non-chemical surface modification as an international patent together with a dental implant material manufacturer as co-inventor (MKM-Engineering GmbH, Offenbach an der Queich, Germany).

As part of the NanoEHS call for proposals, we have been given the opportunity to apply our previous knowledge to a specific question: how do possible abrasions of such ceramics behave? What tent biological effects do we see in our human cell lines and how do our findings compare to conservative dental implants?

Das Projekt wird im Rahmen der 9. nationalen Nano-EHS-Ausschreibung der FFG gefördert: https://projekte.ffg.at/projekt/4822680. CERANANO beschäftigt sich mit der Risikoabschätzung nanopartikulärer Abriebe keramischer Zahnimplantate. Innovative Materialien und Materialkombinationen ermöglichen heutzutage die Herstellung von ästhetischen und zugleich sehr widerstandfähigen Prothesen oder Implantaten für den oralen Bereich. Untersucht wird pulverförmiges, keramischen Material in seiner zellbiologischen Wirkung bis hin zur Zelladhäsion an fertig hergestellten keramischen Zahnimplantaten. CERANANO adressiert somit sicherheits- und gesundheitsrelevante Fragen von innovativen, keramischen Zahnimplantatmaterialien entlang des gesamten Lebenszyklus, um mögliche Wissenslücken an diesen innovativen Medizinprodukten beurteilen und schliessen zu können.


10.11.2023