Department für Biotechnologie (DBT)

Institut für Bioverfahrenstechnik
Institut für Mikrobiologie und Mikrobielle Biotechnologie
Institut für Computergestützte Biologie
Institut für Tierische Zellkultur und Systembiologie
Institut für Zell- und Gewebekultur-technologien
Institut für Molekulare Biotechnologie

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HTPD2023 Minisymposium

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High Throughput Screening & Process Development – how small can we get? Biotech industry has adopted HT screening in micro well plates as process development tools but still the major question remains on how the process can be optimised. Successful application of HT systems for process development depends on the right choice of technology in combination with Design of experiment strategies or mechanistic modelling and statistical evaluation of the obtained data.

Mission Statement

The Department of Biotechnology is a leading institution for research and education, focusing on:

Biotechnology for Health and
Biotechnology for a Sustainable Future.

We develop novel concepts and solutions for the well-being of individuals, society and the environment. Our scientific approaches and methodologies include molecular biotechnology, synthetic biology, bioprocess technology, cell biology, bioanalytics, genome-scale data science, mathematical modeling, as well as techno economic evaluations. By interdisciplinary integration of our scientific results we provide solutions with industrial applicability.

We teach undergraduate and graduate students in all fields of biotechnology mainly in the bachelor program Food- and Biotechnology, the master program Biotechnology, and several Doctoral Schools.

Institutes

Institute of Bioprocess Science and Engineering

Biopharmaceutical processing using E.coli, insects cells, CHO and HEK cells
Model-based control of up and downstream processing
Cyber physical depiction of bioprocesses
Modeling and scale up and scale down of bioprocesses.

Institute of Microbiology and Microbial Biotechnology

Metabolic Engineering
Systems and Synthetic Biology
Cell and Process Engineering
Protein Production and Secretion
Microbial Chemical Production

Institute of Computational Biology

Genome analysis using computational methods
Bioinformatics approaches incl. machine learning
Analysis of high-throughput sequencing data
Genomes of various species, mainly plant

Institute of Animal Cell Technology and Systems Biology

BioProcesses for native and engineered proteins
Protein engineering
Systems biotechnology to understand cellular limitations
Knowledge driven cell line engineering

Institute of Cell and Tissue Culture Technologies

Isolation, characterization, expansion and differentiation of human primary/stem cells for cell-based therapy products
Development of physiologic cell culture conditions mimicking the native cellular environment by using advanced culture technologies
Culture under physioxic conditions
3D culture systems (scaffold-free and scaffold-based)
Culture in dynamic bioreactor systems