Group Pfrengle
Exploring synthetic carbohydrates for plant biology
Using synthetic carbohydrate chemistry, we seek to generate new knowledge on the structure and biosynthesis of plant cell walls as well as plant immunity, which may enable to a more efficient and sustainable usage of crops in the future.
Group Zamyatina
Glycochemistry and Innate Immunity
Our main research interests are in bioorganic chemistry (synthesis of carbohydrate-based biomolecules, glycoconjugates, immunomodulatory glycolipids and various pathogen-associated molecular patterns, as well as carbohydrate vaccines and vaccine adjuvants) to study the host immune response to infection and inflammation.
We are also focusing on the development of unnatural glycan-based biomolecules as tools for investigating the structural and molecular basis of pathogen recognition by the host innate immune receptors.