773108 Practical course in organic chemistry


Type
Exercise course
Semester hours
3
Lecturer (assistant)
Organisation
Offered in
Sommersemester 2021
Languages of instruction
Deutsch

Content

Synthesis and purification of organic substances (extraction, distillation, recrystallization, chromatography)
Criteria of purification (melting point, boiling point, refractive index)
Spectroscopic investigation NMR, IR)
Literature search, safety regulations


Colloquium – table of contents

Basics in organic chemistry (see lecture course organic chemistry for food science and biotechnology), substance categories, reactions and mechanisms in organic chemistry, nomenclature

Purification of substances (preparation in pure form)
•Crystallization
•Sublimation
•Distillation (in vacuum/normal pressure, rectification, azeotropic distillation)
•Standard equipment in organic chemistry
•Separation techniques in organic chemistry (including separation by extraction, based on compound acidity)
•Chromatography (theory, overview) with focus on thin layer and column chromatography.

Purity control
•Determination of melting and boiling point
•Refractive index
•Optical rotation
•Solvent drying

Lab safety
•Safe handling of chemicals (labelling, GHS/CLP, H/P statements, LD50, maximum workplace concentration value)
•Solvents; toxicity, inflammability, labelling, disposal
•Laboratory gas (Nitrogen, Helium, Argon,…) labelling, control armatures

Structure elucidation of organic compounds
•Basics in nuclear magnetic resonance and infrared spectroscopy

Miscellaneous
•Security measures for handling carcinogens and mutagenic substances
•Flammable liquids (handling, precautions, examples)
•Operations in an organic chemistry lab
•Working methods (Installation of experimental apparatus, filtration, recrystallization, distillation, chromatography)
•Use of enzymes in organic chemistry – reductases

Previous knowledge expected

visit of the lecture Organic Chemistry (LBT)

Objective (expected results of study and acquired competences)

basic knowledge in methods of Organic Chemistry as well as in preparation and purification of natural compounds.
You can find more details like the schedule or information about exams on the course-page in BOKUonline.