803017 Modern animal-free biomedicine: of organoids, bioprinting and organs-on-chip


Type
Lecture and seminar
Semester hours
2
Lecturer (assistant)
Rothbauer, Mario
Organisation
Offered in
Sommersemester 2024
Languages of instruction
Englisch

Content

The VS provides students with an overview of approaches to state-of-the-art cell culture technologies as potential alternative methods to animal testing in basic research and drug screening. The course includes a lecture on the basics of dynamic two- and three-dimensional cell culture models consisting of printed tissues, microfluidic bioreactors, organs-on-a-chip and lab-on-a-chip systems. A central focus topic will be the 3Rs (Replacement, Reduction, Refinement) and these will be reflected on together in interactive exercises and homework in various topics of modern disease research. Short excursions into topics such as (bio-)sensor integration, (bio-)interface engineering and the fascinating world of tissue mechanobiology will be taught using concrete examples.

Previous knowledge expected

Basic principles of cell culture (and biotechnology).

Objective (expected results of study and acquired competences)

Students know the basics of microfluidic technologies and dynamic cell culture and can apply them in a problem-oriented manner. Participants recognise advantages and limitations of in vitro alternative methods and can explain them using practical examples. Participants: analyse recent scientific publications and communicate content as a poster presentation and tandem US campaign debate. Basics of literature research and deepening of presentation techniques.
You can find more details like the schedule or information about exams on the course-page in BOKUonline.