940301 Structure and analysis of genomes

Type
Lecture
Semester hours
2
Lecturer (assistant)
Weinhäusel, Andreas , Steinkellner, Herta , Kapusi, Eszter
Organisation
Offered in
Wintersemester 2024/25
Languages of instruction
Englisch
Content

The content of the lecture is a detailed description of the following topics:
(i) Genome structure of Eukaryotes from low to high repetitiveness (single copy genes, gene families, low-, intermediate- and high-repetitive DNA sequences, including retro-transposons)
(ii) Integration of viral sequences into eukaryotic genomes, their structural and functional impact
(ii) Genome wide analyses: the most commonly used molecular techniques and genetic markers for forensic, medical and agricultural purposes.
(iv) Detailed description of Chip-analyses and its use to analyze large amount of genomic data.
(v) Genome wide analysis and next generation sequencing
Please note many lectures are held in an interactive manner, thus it is recommended to physically attend the lecture
Previous knowledge expected

Master level and above
Objective (expected results of study and acquired competences)

Upon attendance of the course students
-) have acquired an overview of eukaryotic genomic elements and how they are organized
-) have a detailed knowledge about the importance of various genetic elements in respect to genome stability and variation.
-) are aware of the importance of virus elements in the eukaryotic genome
-) are familiar with state -of-the art methods in genetic analyses (e.g. microsatellite-analysis, FISH, next sequencing generation, Bio-marker),
-) should be able do chose appropriate genetic markers among others to approach specific questions (individuum identification vs. determination of biodiversity, evolution, etc).
-) are familiar with the enormous potential of chip analyses and genome wide analyses in the “postgenomic area”.
You can find more details like the schedule or information about exams on the course-page in BOKUonline.