834313 Phylogenetic principles in genetic and genomic analysis (in Eng.)
- Vorlesung und Übung
- Vortragende/r (Mitwirkende/r)
- Cardoso Curto, Manuel Antonio
- Angeboten im Semester
- Wintersemester 2019/20
- Unterrichts-/ Lehrsprachen
This course will provide an introduction to phylogenetics analysis using DNA data covering methodologies encompassing both traditional analytical tools and the latest state of the art phylogenomic analysis.
More specifically the course will cover the following topics: introduction to phylogenetics analysis concepts; introduction to sequence technologies; the use sequence data for phylogenetics; different phylogenetic inference methodologies such as parsimony, maximum likelihood, and bayesian approaches; the application of the latest sequencing technologies in phylogenetics and how they contributed to the appearance of phylogenomic; and the latest phylogenomic approaches where concepts such as introgression, coalescent theory, and species tree will be covered.
- Inhaltliche Voraussetzungen (erwartete Kenntnisse)
The class will provide the basic principles of DNA sequence analysis for phylogenetics and genomics.
The students will apprehend the analysis principles for data generation, its assembly and pairwise comparison and properties of different methods. They will know the differences between sequence and codominant datasets and their properties and will be able to decide analysis method in dependance of different datasets. This is the prerequisite to apply the procedures to the different relevant research fields, like animal and plant breeding, biotechnology and conservatoion genetics. In particular the class introduces analysis of high through put genome wide sequence or SNP datasets which will be presented as exercise.
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