790403 Basic course III - expression systems and cell factories (in Eng.)


Art
Vorlesung
Semesterstunden
2
Vortragende/r (Mitwirkende/r)
Mayrhofer, Patrick , Borth, Nicole , Grillari, Johannes , Peterbauer, Clemens Karl , Mattanovich, Diethard , Grabherr, Reingard , Laimer, Margit , Kunert, Renate , Gasser, Brigitte , Steinkellner, Herta
Organisation
Angeboten im Semester
Sommersemester 2021
Unterrichts-/ Lehrsprachen
Englisch

Lehrinhalt

Biologic background
•Regulation of gene expression
•Protein production and stress caused by high-expression levels
•Metabolic engineering
•Strain development and strain optimization, cell banking

Cell Factories covered
•Bacterial cell factories
•Yeast and fungal cell factories
•Plant cell factories
•Mammalian cell factories
•Insect cell factories, Viruses as vectors for recombinant protein production
•Cell-free protein expression systems

Inhaltliche Voraussetzungen (erwartete Kenntnisse)

Basic Course I and II

Lehrziel

A thorough understanding of the different cell factories currently available, of their specific metabolism and their needs as well as their advantages and disadvantages
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