790368 Biological therapeutics (in Eng.)

Art
Vorlesung
Semesterstunden
2
Vortragende/r (Mitwirkende/r)
Kunert, Renate , Radauer, Christian
Organisation
Angeboten im Semester
Wintersemester 2024/25
Unterrichts-/ Lehrsprachen
Englisch
Lehrinhalt

The lecture will take place in seminar room 05/08 in the 5th floor of MUG1/DBT.

If you have any organisational questions, please contact my colleague Christine Prenner (christine.prenner@boku.ac.at)

Kind regards
Renate Kunert

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Contents:

Biological Therapeutics overview
Human Erythropoietin
Human insulin
Therapeutic enzymes
Human growth hormone
Plasma fractionation
Structure and function of immunoglobulins
Development and production of therapeutic antibodies
Recombinant antibody derivatives
Inhibitors of tumor necrosis factor (TNF)
Anti-HER2 and anti-B cell antibodies
Angiogenesis inhibitors
Inhaltliche Voraussetzungen (erwartete Kenntnisse)

students should have passed already the examination cell factories but at least need knowledge about generation of recombinant cell lines and propagation of cell culture
Lehrziel

After having passed the course the students are able
- to transform their scientific knowledge for the development of biological therapeutics
- to assess development strategies and critically evaluate the quality demands of products
- to rank the scale of the production effort for up-stream, down stream and formulation procedures
- to explain data gained by in vitro studies and propose the products behaviour in vivo.
Noch mehr Informationen zur Lehrveranstaltung, wie Termine oder Informationen zu Prüfungen, usw. finden Sie auf der Lehrveranstaltungsseite in BOKUonline.