New Publication in Nature Biotech

The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2. (2019) Gaßler, T., Sauer M., Gasser B., Egermeier M., Troyer Ch., Causon T., Hann St., Mattanovich D., Steiger M. Nature Biotechnology https://doi.org/10.1038/s41587-019-0363-0

New Publication

A time travel story: metagenomic analyses decipher the unknown geographical shift and the storage history of possibly smuggled antique marble statues. (2019), Pinar, G; Poyntner, C; Tafer, H; Sterflinger, K. Annals of Microbiology Vol 69, p 1001-1021. https://doi.org/10.1007/s13213-019-1446-3

New Publication

Back to the Salt Mines: Genome and Transcriptome Comparisons of the Halophilic Fungus Aspergillus salisburgensis and Its Halotolerant Relative Aspergillus sclerotialis. (2019) Tafer, H; Poyntner, C; Lopandic, K; Sterflinger, K; Pinar, G. Genes 2019, 10(5), 381; https://doi.org/10.3390/genes10050381

BOKU Invention Award 2019 for Brigitte Gasser, Diethard Mattanovich, Michael Sauer and Thomas Gaßler

The inventors, Diethard Mattanovich, Brigitte Gasser, Michael Sauer and Thomas Gaßler were able to convince the jury with the "CarboFeed" technology. In this project, a method was developed that makes it possible to process CO2 into an animal feed additive by using a novel yeast. The aim is using CO2 as a sustainable source of raw materials and it also has the eco-friendly effect that no further agricultural land is needed for the production of animal feed.

New Publication

The secretome of Pichia pastoris in fed-batch cultivations is largely independent of the carbon source but changes quantitatively over cultivation time.

Burgard J, Grünwald-Gruber C, Altmann F, Zanghellini J, Valli M, Mattanovich D, Gasser B. (2019) Microb Biotechnol. 2019 Nov 6. doi: 10.1111/1751-7915.13499.

OeGMBT Life Science PhD Award for Thomas Gaßler

At the Life Science Conference of the Austrian Society for Molecular Biosciences and Biotechnology (ÖGMBT), young scientists were honoured for their internationally sensational work - including Thomas Gaßler (DBT) with his work on the biotechnological use of CO2.

Diethard Mattanovich re-elected Vice-President of the European Federation of Biotechnology (EFB).

At the last meeting of the Executive Board of the European Federation of Biotechnology in Barcelona, Diethard Mattanovich was re-elected Vice-President of the European Federation of Biotechnology (EFB).

BOKU Story with Katja Sterflinger-Gleixner

save the date - ICY15 AUG 23-27, 2020

We are all facing a serious situation concerning the corona virus, which makes it unpredictable at the moment how the next months will proceed. Therefore, we all cannot foresee if the plans for ICY15 end of August can hold. - We will keep you updated! www.icy15.org

Latest Publication

A subcellular proteome atlas of the yeast Komagataella phaffii. (2020) Valli M, Grillitsch K, Grünwald-Gruber C, Tatto NE, Hrobath B, Klug L, Ivashov V, Hauzmayer S, Koller M, Tir N, Leisch F, Gasser B, Graf AB, Altmann F, Daum G, Mattanovich D. FEMS Yeast Res. 2020 Feb 1;20(1). pii: foaa001. doi: 10.1093/femsyr/foaa001.

GOLD medal for iGEM Vienna Team @Giant Jamboree 2019 in Boston

The Giant Jamboree is an annual event that showcases work from the iGEM Competition. All iGEM teams were invited to present their synthetic biology projects and compete for prizes in Boston, US. The iGEM Vienna team participated for the third time at this event and we all are proud and happy to say that in 2019 their efforts were rewarded in form of a Gold Medal! - congratulations!

New Publication

Spotlight on biodiversity of microbial cell factories for glycerol conversion.

Russmayer H, Egermeier M, Kalemasi D, Sauer M. (2019) Biotechnol Adv 1;37(6):107395. doi: 10.1016/j.biotechadv.2019.05.001.

New Publication

Recombinant Protein Production in Yeast

This volume provides an overview of the main yeast production platforms currently used and future yeast cell factories for recombinant protein production. Chapters detail approaches of genetic and metabolic engineering, co-factor containing proteins and virus-like particles, glycoproteins, and post-translational modifications of proteins. in: Methods Mol Biol. 2019;1923: ISBN-13: 978-1493990238

Genschalter in Hefe entdeckt

Forschende am Department für Biotechnologie der Universität für Bodenkultur Wien (BOKU) und des Austrian Centre of Industrial Biotechnology (acib) haben einen Genschalter in Hefe entdeckt, der vor Jahrmillionen zwölf Gene gleichzeitig verändert und dadurch den Hefe-Stoffwechselprozess angekurbelt hat. Die in Nature Communications veröffentlichten Forschungsergebnisse bergen großes Potenzial in der Lebensmittelproduktion, der Erzeugung von Biotreibstoffen oder zur Entwicklung von Grundstoffen für Bioplastik.

Latest Publication

Characterization of methanol utilization negative Pichia pastoris for secreted protein production: New cultivation strategies for current and future applications. Biotechnol Bioeng. (2020) Zavec, D; Gasser, B; Mattanovich, D. Feb 8. doi: 10.1002/bit.27303.

Latest Publication

Rapid diagnosis of biological colonization in cultural artefacts using the MinION nanopore sequencing technology, (2020) Pinar, G; Poyntner, C; Lopandic, K; Taferl, H; Sterflinger, K.

https://doi.org/10.1016/j.ibiod.2020.104908 

BOKU Inventor 2019

This year the award BOKU inventor 2019 went ex aequo to Hertha Steinkellner (DAGZ), Reingard Grabherr (Head of Department of Biotechnology) and Brigitte Gasser (DBT). In addition to a cash prize, their commitment and exemplary effect will be rewarded with a personal video presented at the BOKU Autumn Festival at IFA Tulln. - Congratulations!

Rudolf Sallinger Special Award for CarboFeed

The CarboFeed team from the Department of Biotechnology was delighted to receive a special jury prize for their CO2-fixing yeast strain technology at the S&B Award 2019.

Christian Doppler Laboratory for Biotechnology of Glycerol

The CD-Laboratory for Biotechnology of Glycerol is dedicated to the microbial valorization of crude glycerol from biodiesel production.

Christian Doppler Laboratory for Growth-Decoupled Protein Production in Yeast

A report on the CD-lab of Brigitte Gasser in the magazine "Chemiereport 2017-03" (text only available in German).

Transforming CO2 into animal feed

Thomas Gaßler and Michael Egermeier were selected for a FFG Spin-Off Fellowship grant for the transformation of their project “CarboFeed” (Biotechnological production of high-value yeast based animal feed additives from CO2) together with Diethard Mattanovich.

Nature Com. Publication

A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii

(2018) Ata Ö, Rebnegger C, Tatto NE, Valli M, Mairinger T, Hann S, Steiger MG, Çalık P, Mattanovich D. Nature Communications, 9:4911 doi: 10.1038/s41467-018-07430-4

Retrospection: Houska Award 2010