Core Facility Bioactive Molecules Screening & Analysis

The Core Facility Bioactive Molecules: Screening and Analysis (BMOSA) provides high throughput microbiology screening resources and high-end mass spectrometry for a diverse range of molecules.

CF BMOSA is located at the BOKU campus in Tulln.

Covering a broad field of expertise, the facility is separated into a screening and analysis part. 

Find the experts in the field of screening at UFT, the analysis team is located at IFA.

The screening facility provides state-of-the-art hardware, expertise, and robotic liquid handling systems tailored for high-throughput searches of bioactive metabolites and enzymes. We also specialize in characterizing the chemical and biological properties of identified substances. Our services include:

• Investigating interactions between microbes and other organisms (bacteria, fungi, algae, plants, animal cells) to identify bioactive substances (e.g., antibiotics, pharmaceuticals, bioeffectors, agroceuticals).
• Studying microbial metabolomes under diverse environmental and nutritional conditions to uncover bio- and agro-technological potential.
• Analyzing cells of various origins (microbes, plants, insects) for mutual stimulatory or inhibitory effects in a high-throughput manner.
• Exploring host-pathogen interactions and identifying organic control species.
• Screening for biotechnologically relevant enzymes.
• Conducting large-scale microbiology (BSL2 certified) screening experiments.
• Offering purification of bioactive molecules, advanced microscopy, and cellular analysis.

Contact: Christoph Schüller

We offer comprehensive analysis services for a wide range of compounds, with a strong focus on metabolomics. Using advanced equipment and methods, we analyze and quantify primary, secondary, and volatile metabolites. Our expertise includes both targeted analytics and untargeted metabolomics studies, utilizing high-end mass spectrometry to deliver detailed and reliable insights. For untargeted metabolomics, we provide flexible study schemes, including options for data generation only, data evaluation, statistical analysis, and more. Over the years, we have also developed workflows for stable isotope-assisted metabolomics, enabling comprehensive and customized studies.

Our facility is equipped with state-of-the-art mass spectrometers and advanced analytical instruments to support your research. We provide the following services:

• Targeted analytics (qualitative and quantitative)
• Analysis of volatiles
• HPTLC analysis
• Primary metabolite analysis
• Secondary metabolite analysis
• Untargeted metabolomics studies with customizable options (data generation, evaluation, statistics, etc.)

Additionally, we offer to assist in your stable isotope labelling assisted metabolomics experiments including possibility to grow your own labelled plant material.

Contact: Maria Doppler