December 2024
Tom Wennekes from Uetrecht University is guest professor at BOKU in the winter semester 2024/2025. Everybody interested in “Chemical Glycobiology” is invited to sign up in BOKU Online for his course
November 2024
Guest lecture by Tanmay A.M. Bharat - our collaboration partner from the Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK.
Stephanie Walcher publishes her first paper within the frame of the BioToP PhD Programme, in a joint effort with Hanspeter Kählig (University of Vienna) and Johannes Stadlmann (BOKU University).
Deciphering fucosylated protein-linked O-glycans in oral Tannerella serpentiformis: insights from NMR spectroscopy and glycoproteomics. Authors: Stephanie Walcher, Fiona F. Hager-Mair, Johannes Stadlmann, Hanspeter Kählig, Christina Schäffer.
Glycobiology, 2024, Sep 19:cwae072, doi: 10.1093/glycob/cwae072. Online ahead of print.
October 2024
Cordula Stefanović successfully defends her PhD thesis. Congratulations!
Muhammad Afzal and Susanne Bloch from the Schäffer Research Group receive funding from the Hochschuljubiläumsfonds der Stadt Wien for the research project “Is the lipopeptide mutanobactin an inhibitor of health-associated oral bacteria?”
September 2024
Cordula Stefanović publishes her fourth paper within the frame of the BioToP PhD Programme, in a joint effort with our collaboration partners from the University of Victoria and the Oostenbrink group (BOKU University). Authors: Cordula Stefanović, Max S.G. Legg, N. Mateyko, Jakob J. Ender JJ, Tea Kuvek, Chris Oostenrink C, Christina Schäffer, Stephen V. Evans, Fiona F. Hager-Mair.
Frontiers in Molecular Bioscience, 2024, 11:1470989. doi: 10.3389/fmolb.2024.1470989
August 2024
Fabian Kendlbacher publishes his second paper within the frame of his PhD thesis.
Red-complex bacteria exhibit distinctly different interactions with human periodontal ligament stromal cells compared to Fusobacterium nucleatum. Authors: Fabian L Kendlbacher, Susanne Bloch, Fiona F Hager-Mair, Christina Schäffer, Oleh Andrukhov.
Archives in Oral Biology, 2024. 164:106004. doi: 10.1016/j.archoralbio.2024.106004.
July 2024
Investigating the role of a Tannerella forsythia HtrA protease in host protein degradation and inflammatory response. Authors: Susanne Bloch, Fiona F Hager-Mair, Johanna Bacher, Markus B Tomek, Bettina Janesch, Oleh Andrukhov, Christina Schäffer
Frontiers in Oral Health, 2024, 5:1425937. doi: 10.3389/froh.2024.1425937.
May 2024
The intriguing strategies of Tannerella forsythia's host interaction. Authors: Christina Schäffer, Oleh Andrukhov.
Frontiers in Oral Health, 2024, 5:1434217. doi: 10.3389/froh.2024.1434217.
April 2024
The Schäffer Research Group publishes a review article on the “Glycolanguage of the oral microbiota”. Authors: Susanne Bloch, Fiona F. Hager-Mair, Christina Schäffer
Molecular Oral Microbiology, 2024, 39(5):291-320, doi: 10.1111/omi.12456.
February 2024
The Schäffer Research Group together with Oleh Andrukhov (Medical University of Vienna) publishes a review article on “Oral streptococci: modulators in health and disease” Authors: Susanne Bloch, Fiona Hager-Mair, Oleh Andrukhov, Christina Schäffer.
February 2024
Fiona Hager-Mair, PhD and Dipl.-Ing. Cordula Stefanovic from the Schäffer Group present their research at the 27. AustroCarbNet Workshop at TU Graz, Austria:
Presentation titles:
- “UDP-GlcNAc-2-epimerase MnaA, an enzyme central to glycoconjugate biosynthesis”,
- “LytR-CpsA-Psr glycopolymer transferases, an essential step in Gram-positive cell wall assembly”
Cooperation partners Prof. Hanspeter Kähling (University of Vienna) and Dipl.-Ing. Michael Bruckner (BOKU) present their work on:
- “How to resolve complex carbohydrate NMR spectra (S-layer O-glycan from Tannerella serpentiformis”,
- “Synthesis of probes and inhibitors for SCWP-mediated S-layer glycoprotein anchoring”
January 2024 – April 2024:
Stephanie Walcher spends a research stay abroad in Utrecht (the Netherlands) in the Computational Structural Biology group of Alexandre Bonvin within the frame of her PhD thesis and as part of the BioToP PhD programme. She creates a model of the Tannerella serpentiformis S- layer, composed of two surface layer proteins, using HADDOCK 2, an information-driven flexible docking approach that was developed in A. Bonvin’s lab for the modeling of biomolecular complexes.
November 2023
Stephanie Walcher, MSc. from the Schäffer Group presents her research at the Society for Glycobiology Meeting 2023, Waikaloa, Big Island, Hawaii, USA.
Presentation title: “Elucidating the O-glycan structure of the novel periodontal health-associated bacterium Tannerella serpentiformis”
September 2023
Prof. Christina Schäffer is invited to the 3rd International Conference on Oral Mucosal Immunity and Microbiome, Crete, Greece.
Title of lecture: “Tannerella species in periodontal health versus disease”
June 2023
Prof. Christina Schäffer is invited to the Beilstein Symposium Glycobioinformatics, Limburg, Germany.
Title of lecture: “S-Layer glycosylation patterns of Tannerella species in oral health versus disease”
Stephanie Walcher, MSc. presents her work on Tannerella serpentiformis at the same conference.
February 2023
The Schäffer Research Group together with BOKU project partners published a paper in Nature on “Molecular modelling and site-directed mutagenesis provide insight into saccharide pyruvylation by the Paenibacillus alvei CsaB enzyme”. Authors: Cordula Stefanović, Fiona Hager-Mair, Erik Breslmayr, Arturo López‑Guzmán, Charlie Lim, Markus Blaukopf, Paul Kosma, Chris Oostenbrink, Roland Ludwig, and C. Schäffer
October 2022
Christina Schäffer (BOKU Vienna), Chris Oostenbrink (BOKU Vienna) and Markus Blaukopf (BOKU Vienna) receive 596.000 € funding from the FWF for the research project “Structural glycobiology and inhibition of S-layer anchoring by secondary cell wall glycopolymers”. Collaborators in this project are Paul Kosma (BOKU Vienna), Stephen V. Evans (University of Victoria, CAN) and Tanmay Bharat (University of Oxford, UK).
October 2022
Christina Schäffer is promoted to the rank of Univ.Prof. for “Molecular Glycobiology” at BOKU Vienna, Department of Chemistry.
September 2022
Susanne Bloch, PhD returns to the Schäffer Research Group after maternity leave as a postdoctoral researcher with a dual affiliation at BOKU Vienna and at the Competence Center Periodontal Research, University Clinic of Dentistry, Medical University of Vienna, Austria.
August 2022
The Schäffer Research Group together with O. Andrukhov (Medical University of Vienna) and T. Thurnheer (University of Zurich) publish “Multispecies biofilm behavior rand host interaction support the association of Tannerella serpentiformis with periodontal health” Authors: Fabian. L. Kendlbacher, Suanne Bloch, Fiona F. Hager-Mair, Johanna Bacher, Bettina Janesch, Thomas Thurnheer, Oleh Andrukhov, and Christina Schäffer. Molecular Oral Microbiology, 2022; 1-19.
July 2022
Fiona Hager, PhD and Stephanie Walcher, MSc. from the Schäffer Group present their research work at the 25. AustroCarbNet Workshop at TU Graz, Austria.
May 2022
Dipl.-Ing. Cordula Stefanović from the Schäffer Group wins prestigious ÖAW Doc Fellowship to perform her PhD research project “Enzymatic ligation of pyruvylated secondary cell wall glycopolymer to peptidoglycan as an essential step for bacterial cell wall assembly”.
April 2022
Fiona Hager-Mair, PhD gives her first lecture on “Antimicrobials” within the frame of BOKU’s course LV 772.330 “Microbiology and Disease”.
December 2021
Christina Schäffer (BOKU Vienna), Erick M. Carreira (ETH Zurich) and Erik Reimhult (BOKU Vienna) receive 610.000 € funding from the WWTF within the frame of the 2021 Life Science Call “Chemical Biology” for the interdisciplinary research project “Mutanofactin – A molecular adhesive in cariogenic microbial biofilms?”
