Recent Publication Highlights

Halide binding by myeloperoxidase is regulated by access channel dynamics and charge interactions
Urban Leitgeb, Radek Crha, Isabella Fegerl, Paul G Furtmüller, Chris Oostenbrink, Vera Pfanzagl, 2025
X-ray–induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner
Vera Pfanzagl, John H Beale, Hanna Michlits, Daniel Schmidt, Thomas Gabler, Christian Obinger, Kristina Djinović-Carugo, Stefan Hofbauer, 2020
Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal structure and biochemical characterization
Vera Pfanzagl, Clemens Gruber-Grünwald, Urban Leitgeb, Paul G. Furtmüller, Christian Obinger, 2023
Reaction of human peroxidasin 1 compound I and compound II with one-electron donors
Benjamin Sevcnikar, Martina Paumann-Page, Stefan Hofbauer, Vera Pfanzagl, Paul G. Furtmüller, Christian Obinger, 2020
The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation
Urban Leitgeb, Paul G. Furtmüller 1, Stefan Hofbauer, Jose A. Brito, Christian Obinger, Vera Pfanzagl, 2022