Simon Streib completed his BSc in Molecular Biology (2019) and MSc in Biotechnology (2023) at the University of Basel and ETH Zürich. His master’s thesis examined stem‑cell–derived brain organoids, assessing how Matrigel and agarose encapsulation shape identity and regional patterning, and included engineering a blood–brain barrier endothelial stem‑cell line through a transcription‑factor overexpression screen analyzed by single‑cell RNA sequencing.
Simon also complemented his studies with industry internships at Novo Nordisk in Denmark (2021–2022), contributing to pancreatic differentiation research, and at Sentec AG in Switzerland (2023), helping develop a transcutaneous CO2 sensor.
From 2024–2025, Simon was a technician at Osaka University, advancing an extracorporeal liver therapy program. He scaled liver organoid differentiation from plate formats to stirred‑tank bioreactors such as Eppendorf BioFlo and the automated Ambr 250 HT, and developed early bioprocess strategies to transition challenging differentiation workflows to 3D suspension systems.
Since 2026, he has been with the Institute of Cell and Tissue Culture Technologies (ICTCT) at BOKU, where he plans to pursue a PhD on engineering a scalable 3D mesenchymal stem cell (MSC) culture system for extracellular vesicle (EV) production.
