The Thermo Scientific Orbitrap IQ-X Tribrid mass spectrometer is designed to reveal complex chemical structures for compound identification and structure elucidation of small molecules. The system allows for detection and characterization of more low-abundance analytes in complex matrices. The system is used for targeted and non-targeted analysis of small molecules.

Technical Information

Orbitrap IQ-X Tribrid LC-MSn. Thermo Fisher Scientific GmbH. Obtained 2023.

The Thermo Scientific Orbitrap IQ-X Tribrid is equipped with a Vanquish Horizon UHPLC with UV and fluorescence detectors as well as a fraction collector.

A segmented quadrupole mass filter enables higher transmission at narrower isolation width down to 0.4 m/z, improving sensitivity and selectivity.

The ultra-high field Orbitrap analyzer can achieve resolutions up to 500,000 at m/z 200, distinguishing between ions of interest and interfering ions for fine isotope structure.

The dual-pressure linear ion trap provides MSⁿ rates of up to 45Hz and sensitive mass analysis of three complementary fragmentation types: CID, HCD and UVPD.