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Latest Projects

Research project (§ 26 & § 27)
Duration : 2011-01-01 - 2012-02-21

Different species of Pseudomonas are used as plant protecting agents especially to bate potatoes. To achieve an admission from the authorities the Pseudomonas strains must be tested for their toxicological properties. To circumvent animal studies, test systems are developed to analyse the harmful potential on in vitro cultures of lung epithelial cells. Therefore Calu-3 cells are grown on transwell plates until tight junctions are formed. To classify the bacterial strains, the integrity of the tight junction is evaluated after incubation of Pseudomonas with cell cultures.
Research project (§ 26 & § 27)
Duration : 2018-12-01 - 2019-11-30

Demographic changes in the industrialized world lead to an increased occurrence of medical conditions, for which biological age is the major risk factor. In addition to arising complications and onset of multimorbidity due to decreased resilience, frailty severely limits the quality of life at advanced age. Thus, a better understanding of biological ageing processes will promote the design of interventions, which target biological ageing and thereby increase fitness, decrease frailty and improve resilience at advanced age. However, simple and cost-effective models of human healthspan are still missing. Thus, we will establish standardized and reproducible tests for evaluating mobility, memory and electrophysiology of ageing nematodes. With these methods we will evaluate if known interventions extending lifespan also improve physiology at advanced age.
Research project (§ 26 & § 27)
Duration : 2019-04-01 - 2020-09-30

One of the main challenges of the next century is the CO2 emission reduction in a sustainable way in order to mitigate climate change. Further, the increasing food demand of the growing world population has to be covered under preservation of the diversity of natural ecosystems. Our aim is to tap CO2 as a sustainable resource in order to provide a commercial solution for the climate issue. With a novel yeast strain, CO2 can be converted into high-value biomass which is used as an animal feed additive, without using agricultural area.

Supervised Theses and Dissertations