Auszeichnung für Glycobiologie
Dipl.-Ing. Johannes Führer currently doctoral student at the Department of Chemistry, Division of Biochemistry, Glycobiology-group, BioTop, has won the FEBS Letters-poster award at the 24th International Symposium on Glycoconjugates (Glyco24) in Jeju, Korea.
The Glyco-symposium are the leading international conference series in the area of glycobiology and
glycochemistry. Dipl.-Ing. Johannes Führer received the award for his work on "Enzymatic stable isotope labelling of small
O-glycans for improved tumor biomarker analysis". This work aims to improve the detection of biomarker
Using the isomer specific analysis method porous graphitic carbon coupled the electrospray mass
spectrometry. Crucial for this approach ist the enzymatic elongation of the Tn-antigen found on mucins and other secreted proteins by the incorporation of 13C6-labelled galactose using recombinantly expressed ß-1, 3-galactosyltransferase.