Core Facility Biomolecular & Cellular Analysis

The BOKU Core Facility Biomolecular & Cellular Analysis (BMCA) is a state-of-the-art analytical laboratory specializing in biomolecular characterization, the investigation of biomolecular interactions, protein crystallography, and flow cytometry.

In addition to advanced instrumentation, we provide the possibility for you to prepare your samples in the most optimal way. We offer essential laboratory equipment and two PC workstations that are accessible to all Core Facility users, allowing access to the specialized (licensed) software for the various instruments.

Along with equipment access, we offer professional training in specific techniques and consultations on experimental setup and design. Additionally, we provide a full-service option, which includes sample measurements performed by trained staff and the generation of detailed experimental reports.

Biomolecular analysis

A strong focus lies on the investigation and characterization of various biomolecular interactions. To support this, we are equipped with:

To characterize biomolecules in terms of molecular weight, thermal stability, thermodynamics of unfolding, aggregation behaviour, size and zeta potential, the following equipment is available:

For purification of protein samples, you can book our:

Protein purification (AEKTA go, Cytiva).

Cellular analysis

As our name suggests, we also provide techniques for analyzing cells and cellular components, primarily through flow cytometry. Additionally, we have two FACS (Fluorescence-Activated Cell Sorting) machines, allowing for precise and efficient cell sorting for applications such as functional assays, single-cell analysis, and purification:

Protein crystallization

Another key area of our Core Facility is protein X-ray crystallography. We offer state-of-the-art infrastructure for protein crystallization and subsequent analysis. For this, we are equipped with:

In addition, we provide tools and equipment for crystal harvesting, freezing, storage, and dry shippers for sending crystals to the synchrotron. The shipment of crystals and data collection are included in our service.