SUPERVISOR: Georg GÜBITZ

PROJECT ASSIGNED TO: Bettina SEMLER

This project will investigate in detail the hydrolysis reactions of novel bio-based plastics based on 2,5-FDCA through well characterized and novel enzymes produced in either prokaryotic or eukaryotic systems. The research will be performed in the context of FURIOUS (Versatile FUran-based polymeRs for strIct and high value applicatiOns in packaging, aUtomotive and underwater environmentS) European project, which addresses the development of versatile polymers to enrich the portfolio of bio-based materials that can replace traditional plastics.

The novel materials will be designed for three areas in which traditional plastics are still widely used: biomedical and electronic packaging, the automotive sector and underwater devices.

Within the context of the EU research project, this doctoral dissertation seeks to evaluate the recyclability, compostability, and biodegradability of a material with the goal of waste reduction. The focus is on optimizing the enzymatic hydrolysis of polyesters, where various parameters will be adjusted during the application of previously utilized enzymes such as cutinases in PET hydrolysis. Additionally, the research will explore the identification of new enzymes from microbial communities, employing transcriptomic and proteomic methodologies. This aims to enhance the repertoire of tools available for biofunctionalization and processing of polyesters.