List of ongoing doctoral research projects sorted by department: 

Department of Biotechnology (DBT)

Adjusting membrane permeability for extracellular peptide production in growing Escherichia coli

Project assigned to: Martin Gibisch
Supervisor: Gerald Striedner

Advance Analytics of recombinant AAVs for gene therapy vectors

Project assigned to: Sabrina Leigheb
Supervisor: Astrid Dürauer

Alternative pathway design for the mixotrophic production of chemicals from CO2 in Pichia pastoris

Project assigned to: Golnaz Memari 
Supervisor: Diethard Mattanovich 

Cell engineering for AAV production

Project assigned to: Maria Toth
Supervisor: Astrid Dürauer 

Characterization of Bionanoparticles by biophysical methods

Project assigned to: Viktoria Mayer
Supervisor: Alois Jungbauer

Characterization of HEK293 cell lines for rAAV production

Project assigned to: Georg Smesnik
Supervisor: Nicole Borth, Astrid Dürauer

CO2-negative bioproduction of value-added organic acids using engineered strains of the established Pichia pastoris yeast 

Project assigned to: Manja Mølgaard Severinsen
Supervisor: Diethard Mattanovich 

Continuous separation of recombinant antibodies by non‑chromatography methods

Project assigned to: Gregory Dutra 
Supervisor: Alois Jungbauer 

Development of control concepts and integrated solutions in a fully continuous and automated End-to-End manufacturing process platform of biopharmaceuticals focused on the upstream part 

Project assigned to: Magdalena Pappenreiter 
Supervisor: Alois Jungbauer

Development of high titre soluble expression systems for recombinant protein expression in Escherichia coli via the application of solubility tags and the utilisation of phage derived 5’ UTR expression enhancers 

Project assigned to: Christoph Köppl 
Supervisor: Gerald Striedner 

Development of methods for in vivo quantification of proteolysis in E. coli expression systems

Project assigned to: Hana Hanaee Ahvaz
Supervisor: Gerald Striedner

Downstream development for an integrated continuous manufacturing process for monoclonal antibodies 

Project assigned to: Gabriele Recanati  
Supervisor: Alois Jungbauer

Economic and ecological assessment of clean water for biopharmaceuticals

Project assigned to: Alessandro Luigi Cataldo
Supervisor: Alois Jungbauer

Economic and ecological evaluation of new processing schemes for the enzymatic treatment of non-recycled plastic fractions 

Project assigned to: Tommaso De Santis 
Supervisor: Gerald Striedner 

Fed-batch and continuous production of PET degrading enzymes in E.coli 

Project assigned to: Lisa Fohler 
Supervisor: Gerald Striedner

Fully integrated continuous bioprocessing of recombinant proteins using mammalian cells

Project assigned to: Daniel Paul Komuczki
Supervisor: Alois Jungbauer

Functionalised non-woven nanofibers for the purification of Virus-like particles (VLPs) in Biotechnological Downstream Processing

Project assigned to: Alexander Zollner 
Supervisor: Alois Jungbauer

Function, Control and Engineering of Microbial Methylotrophy, FUNCEMM

Project assigned to: Xavier Farge
Supervisor: Diethard Mattanovich 

Host cell response to antibody fragment production in E. coli with special focus on transcriptome and translatome

Project assigned to: Sophie Anna Vazulka
Supervisor: Gerald Striedner

Hybrid modeling of cross flow filtration for biopharmaceutical production

Project assigned to: Maximilian Krippl
Supervisor: Astrid Dürauer 

Impact of mass transfer mechanism on protein separation in two-component adsorption

Project assigned to: Jürgen Beck 
Supervisor: Rainer Hahn 

Increasing the carbon efficiency of citric acid production 

Project assigned to: Evelyn Carolina Vásquez Castro
Supervisor: Diethard Mattanovich 

Influence of fermentation strategies and scale effects on Fab fragment production in Escherichia coli

Project assigned to: Florian Mayer
Supervisor: Gerald Striedner

Investigation and metabolic modelling of glycosylation in chinese hamster ovary (cho) cells 

Project assigned to: Jerneja Štor
Supervisor: Nicole Borth 

Metabolism of Yarrowia lipolytica growing as a biofilm 

Project assigned to: Akarawit Jenjitwanich 
Supervisor: Michael Sauer

Microbial Upgrading of a carbon-rich by-product in cellulose fiber production 

Project assigned to: Robin Hoheneder
Supervisor: Michael Sauer

Microfluidic platform for downscaling fermentation and for screening engineered strains

Project assigned to: Damiano Totaro
Supervisor: Diethard Mattanovich

MISTER - Metabolic lncorporation of latent fast reacting thioeSTERs

Project assigned to: Arshia Arasteh Kani
Supervisor: Gerald Striedner

Model based process development and scale up of primary recovery for biopharmaceutical production 

Project assigned to: Markus Berg 
Supervisors: Rainer Hahn, Astrid Dürauer 

Nanomembranes for in-situ removal of products from fermentation broth 

Project assigned to: Mafalda Silva dos Santos 
Supervisor: Alois Jungbauer

Next generation flocculants for intensified monoclonal antibody production

Project assigned to: Anna Frank
Supervisor: Rainer Hahn 

Omics-Driven Optimisation of CQAs in Industrial CHO Fed-Batch Bioprocessing

Project assigned to: Larissa Hofer 
Supervisor: Nicole Borth 

Online Monitoring in Downstream Processing of AAVs 

Project assigned to: Martina Winter 
Supervisor: Astrid Dürauer

Optimization of industrially applicable microbial 1,3-propanediol and 3-hydroxypropionic acid production

Project assigned to: Irene Tomico Cuenca
Supervisor: Diethard Mattanovich 

Power input in miniaturized systems for continuous operation 

Project assigned to: Ignacio Montes Serrano 
Supervisor: Astrid Dürauer  

Process development of an integrated continuous two-stage chemostat manufacturing platform using growth-decoupled Escherichia coli

Project assigned to: Florian Simon
Supervisor: Gerald Striedner

Production of acetic acid from methanol and CO2: a fermentation approach

Project assigned to: Clara Goldin
Supervisor: Diethard Mattanovich 

Process development for high yield fermentation of active recombinant lectins expressed in Escherichia coli

Project assigned to: Natalia Danielewicz
Supervisor: Gerald Striedner

Process optimization for the biosynthesis of non-canonical amino acids

Project assigned to: Claudia Lacombe
Supervisor: Gerald Striedner

Production of 3-hydroxypropionic acid with Lactobacillus diolivorans 

Project assigned to: Stefan Ergoth 
Supervisor: Michael Sauer

Purification of recombinant secretory immunoglobulin A and its biophysical and biochemical characterization

Project assigned to: David Scheich
Supervisor: Rainer Hahn 

Recombinant protein extraction with Polymers

Project assigned to: Jürgen Beck 
Supervisor: Alexander Jurjevec

Residence time distribution (RTD): effect on start-up and shut-down for product collection 

Project assigned to: Narges Lali 
Supervisor: Alois Jungbauer

Scenarios for Improvement of Green Metrics for Biologics

Project assigned to: Felix Dieringer
Supervisor: Alois Jungbauer

Semi-automation of bioanalyses for real-time monitoring of quantity, purity and activity of biopharmaceuticals

Project assigned to: Anna Christler
Supervisor: Alois Jungbauer

Targeted evolution for continuous production in Escherichia coli

Project assigned to: Stephan Gutmann 
Supervisor: Gerald Striedner

Unravelling the glycerol metabolism of Yarrowia lipolytica 

Project assigned to: Anna Erian 
Supervisor: Michael Sauer

Virus-like particle production in insect cells 

Project assigned to: Lena Achleitner 
Supervisor: Alois Jungbauer

Department of Landscape, Spatial and Infrastructure Sciences

Novel machine learning methods in bioprocess engineering 

Project assigned to: Matthias Medl 
Supervisor: Friedrich Leisch